Disparities in mortality among 25-44-year-olds in England: a longitudinal, population-based study.

Since the mid-1990s in England, there has been a marked trend of increasing excess mortality in the north for those aged 25–44 years, which, until recently, was concealed in the mortality statistics for the wider English population. 5 This north–south divide first began to emerge in the mid-1990s, and the mortality was 40% higher in the north than in the south by 2015. 5 Deaths in this age group are most commonly attributable to cardiovascular disease; accidents; and suicide, poisoning, and the sequelae of drug and alcohol misuse.

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