At t = 8, also the percentages of CD4 T cell subsets, and proliferating nTregs were comparable to baseline, nevertheless, the percentages of proliferating CM CD8 T cells were significantly increased and the TEMRA CD8 T cell population showed a trend towards an increase ( Figure 3E ).
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Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy.
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