showed a trendp = 0.06
The results showed a trend towards reduced lipid peroxidation (3.5±2.4% vs 5.6±3.7%, p = 0.06, HMGB1 vs control) while superoxide production was significantly reduced in the HMGB1 group compared with control (219±32 units/mm 2 vs 1185±97 units/mm 2 , respectively, p<0.0001) ( Fig 8 ).