Anti-Myelin Oligodendrocyte Glycoprotein and Human Leukocyte Antigens as Markers in Pediatric and Adolescent Multiple Sclerosis: on Diagnosis, Clinical Phenotypes, and Therapeutic Responses.

Despite the extensive literature regarding adult MS, they concluded that—while the generally observed higher burden did not reach statistical significance—the weighted genetic risk score of these mutations was significantly associated with pediatric-onset MS [ 77 ]. 3.

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