showed a trendP = 9.2 × 10 −7
In contrast, rs187522732, located in the intergenic region between KCNJ3 and NR4A2 , showed a trend toward a significant association (effect size = 0.0713 [SE = 0.0145], P = 9.2 × 10 −7 ) in the discovery phase, but not in the replication phase ( P = 0.51).The combined P value for this variant in the meta-analysis ( P = 8.2 × 10 −6 ) was higher than that in the discovery phase, indicating that this association is likely a false positive.