After induction of nephritis, F4/80 + cells around glomeruli increased in Vangl2 flox/flox ( p < 0.01) and PodCre + /Vangl2 flox/flox kidneys, although in the latter case, this did not reach statistical significance ( p = 0.06), but there was no difference between genotypes.
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Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.
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