A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease.

Alzheimers Res Ther · 2018 · PMC6286509 · PMID 30526652

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0.1000

closest p · 2.0× alpha

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The sentences

did not reach statistical significancep value = 0.1so close (0.05 < p ≤ 0.1)

However, in the small sample size that was studied, this effect did not reach statistical significance (Fisher p value = 0.1).

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