Systematic identification of mutations and copy number alterations associated with cancer patient prognosis.

CDKN2A deletion is a strong indicator of poor prognosis in the pan-kidney cohort, in clear cell carcinomas, and in papillary cell carcinomas, but did not reach statistical significance when kidney chromophobe carcinomas were analyzed independently ( Figure 2—figure supplement 4F–G ).

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Overall, we observed a highly significant correlation between the meta-Z scores obtained from the TCGA and cBioportal datasets (R = 0.42; Figure 4H ).

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