ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease.

J Biol Chem · 2018 · PMC6290164 · PMID 30315100

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did not reach statistical significanceno p-value reported

As we reported previously ( 21 ), we observed that total APP was higher in 5XFAD females than in 5XFAD males, although in this cohort, the difference did not reach statistical significance (data not shown).

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a nonsignificant trendno p-value reported

At 6 and 9 months, as at 4 months, there was a nonsignificant trend toward higher APP in female compared with male 5XFAD mice (data not shown).

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