Investigating Multimodal Diagnostic Eye Biomarkers of Cognitive Impairment by Measuring Vascular and Neurogenic Changes in the Retina.

Front Physiol · 2018 · PMC6291749 · PMID 30574092

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showed a trendno p-value reported

Although individuals with cognitive impairment showed a trend toward a higher length diameter ratio (LDRa, LDRv, and LDRt), this difference was not statistically significant.

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a statistical trendno p-value reported

This study illustrates that there are multimodal retinal markers that may be sensitive to CI decline, and adds to the evidence that there is a statistical trend pointing to the correlation between retinal neuronal dysfunction and microvasculature changes suggesting that retinal geometric vascular and functional parameters might be associated with physiological changes in the retina due to CI.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.