Mitochondrial gene sequence variants in children with severe malaria anaemia with or without lactic acidosis: a case control study.

Malar J · 2018 · PMC6293624 · PMID 30545357

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hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

did not quite reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

In particular, non-synonymous variants predictive to disrupt at least one member of the NADH dehydrogenase gene cluster were twice as common in children with high lactates, a finding that did not quite reach statistical significance (p = 0.052).

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did not reach statistical significanceno p-value reported

Although the comparisons did not reach statistical significance for the sample size tested, the average number of non-synonymous variants per individual, the number of individuals with non-synonymous variants, and the occurrence of variants predicted to cause protein disruption were all higher in the group with elevated blood lactate levels.

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