Barely Significant
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Al-hijamah (wet cupping therapy of prophetic medicine) significantly and safely reduces iron overload and oxidative stress in thalassemic children: a novel pilot study.

J Blood Med · 2018 · PMC6300367 · PMID 30588142

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quite significantno p-value reported
7 , 8 Although the clearance is partial in many conditions, it is quite significant, therapeutically beneficial and can be increased via increasing the number of sucking cups and Al-hijamah sessions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.