Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002.

Infect Immun · 2019 · PMC6300642 · PMID 30323028

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showed a trendno p-value reported

While IL-6, MCP-1, and KC were significantly upregulated in the serum and TNF-α showed a trend toward upregulation, only the genes for MCP-1 and TNF-α were significantly upregulated in the blood, probably reflecting differences in kinetics for these cytokines and chemokines and/or mobilization of some cytokines from the lung into the blood.

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