The contralateral hind paw mechanical threshold decreased by day 10 to 65% of baseline indicating sensiziation but this did not reach statistical significance compared with respective baseline ( p = 0.056) nor compared with non-inflamed controls ( p = 0.071), when analysed by 2-way ANOVA + post hoc analysis Fig. 1 d).
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VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis.
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