Haplotypes in the CYP2R1 gene are associated with levels of 25(OH)D and bone mineral density, but not with other markers of bone metabolism (MrOS Sweden).

PLoS One · 2018 · PMC6303094 · PMID 30576350

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a clear trendno p-value reported

For the other SNPs, no significant differences in BMD were found between SNP genotypes, but there was a clear trend for all SNPs that lower 25(OH)D levels were associated with higher BMD values ( Fig 2 ).

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