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Enhanced Oxidative Damage and Nrf2 Downregulation Contribute to the Aggravation of Periodontitis by Diabetes Mellitus.

Oxid Med Cell Longev · 2018 · PMC6304894 · PMID 30622677

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The serum MDA level and SOD activity of the P and C groups did not reach statistical significance, which may be due to the tissue-preserving antioxidant-adaptive mechanism against the oxidative stress developed in periodontitis [ 17 ].

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