The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase.

EBioMedicine · 2018 · PMC6306395 · PMID 30497978

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did not reach statistical significanceno p-value reported

The levels of BiP were significantly increased by 100 μM and 200 μM arimoclomol in GM10915 [L444P/L444P] cells, by 200 μM and 400 μM arimoclomol in GM01607 [N370S/V394L] cells, whereas the minor increases in GM02627 [G325R/C342G] cells did not reach statistical significance.

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