showed a trendP = 0.077
Comparing the IRS values for DVL2 and DVL3, statistically significant negative correlation was established only for pilocytic astrocytomas ( r = −0.699, t = −3.388, P = 0.005), while anaplastic astrocytomas showed a trend of negative correlation for the two proteins ( r = −0.488, t = 0.236, P = 0.077) (Figure 5 C).