Barely Significant
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N-terminal transactivation function, AF-1, of estrogen receptor alpha controls obesity through enhancement of energy expenditure.

Mol Metab · 2018 · PMC6308972 · PMID 30287090

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The tissue weight of visceral fat in the placebo-treated OVX WT and intact AF2ERKI, compared to intact WT animals, was higher, but this did not reach statistical significance.

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