Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.

Although the latter difference did not reach statistical significance, a K means cluster analysis revealed that the difference in the distribution of mouse genotypes with respect to these parameters was indeed statistically different, with WT mice associated with the SP-D–low/IL-6–high cluster and uPARAP knockout mice in the SP-D–high/IL-6–low cluster ( Fig. 5 F ).

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