The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis.

Arthritis Res Ther · 2019 · PMC6322248 · PMID 30612576

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did not reach statistical significanceno p-value reported

Interestingly, under basal conditions, Bmal1 loss results in increased secretion of several pro-inflammatory cytokines (e.g., CCL2 and CXCL5), but this did not reach statistical significance.

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