Characterization of Corneal Epithelial Cells in Keratoconus.

Concurrently, mRNA expression of Notch downstream target hes3 levels was significantly increased in the extraconal periphery epithelial cells and showed an increasing trend with increasing grades of the disease severity.

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The extraconal periphery showed a trend of increasing levels of VIMENTIN with increasing severity of KC, whereas the cones did not show much change with respect to the controls ( Fig. 3Dii ).

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