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Identifying genes with tri-modal association with survival and tumor grade in cancer patients.

BMC Bioinformatics · 2019 · PMC6323748 · PMID 30621577

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The phenotype of ORMDL3 amplification may be artefact of nearby ERBB2 expression Overall, we conclude that both the up-regulation and down-regulation of ORMDL3 were correlated with bad prognosis and higher tumor grade in breast cancer patients, although this observation did not reach statistical significance in some small validation datasets.

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