Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still's disease.

Arthritis Res Ther · 2019 · PMC6323819 · PMID 30616678

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did not reach statistical significanceno p-value reported

The expression levels of IL-18 were upregulated in THP-1 cells with AOSD NET DNA treatment compared with healthy controls; however, this difference did not reach statistical significance (Fig. 4 a).

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