A correlative trend between plasmablast and CXCR3 + PD1 hi CD4 + T cell frequencies was found, but it did not reach statistical significance ( Supplementary Fig. 7b, c ) most likely due to plasmablast fragility during cryopreservation.
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A CD4<sup>+</sup> T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate.
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