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Sex hormone-binding globulin provides a novel entry pathway for estradiol and influences subsequent signaling in lymphocytes via membrane receptor.

Sci Rep · 2019 · PMC6327036 · PMID 30626909

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SHBG staining tended to decrease in T cells obtained from pregnant women as well, although it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.