tended towards significanceP = 0.06
Neither showed a significant change in concentration in plasma for the two genotypes, although an increase in cholesta-4,6-dien-3-one in the Cyp27a1−/− animal tended towards significance (0.21 ± 0.05 μg/mL cf. 0.07 ± 0.08 μg/mL, P = 0.06).