The risk of subsequent osteoporotic fractures is decreased in subjects experiencing fracture while on denosumab: results from the FREEDOM and FREEDOM Extension studies.

Osteoporos Int · 2019 · PMC6331737 · PMID 30244369

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did not reach statistical significanceno p-value reported

However, in subjects without baseline vertebral fracture, the size of the denosumab treatment effect was smaller compared with subjects with baseline vertebral fracture, and it did not reach statistical significance.

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