The Cox proportional hazards model showed a trend that OTUB2 (χ 2 =2.911, Risk Ratio = 1.306), U2AF2 (χ 2 = 1.601, Risk Ratio = 1.319) and PGK1 (χ 2 = 1.668, Risk Ratio = 1.551) were independent prognostic variables in NSCLC patients.
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OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer.
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