Prevalence and Prognostic Role of PIK3CA/AKT1 Mutations in Chinese Breast Cancer Patients.

While patients with 1MT in PIK3CA/AKT1 showed a trend toward better iDFS than patients with WT PIK3CA/AKT1 (p=0.054) ( Fig. 1C ), the OS of patients with 1MT in PIK3CA/AKT1 was not significantly different than in patients with WT PIK3CA/AKT1 ( Fig. 1D ). 2) ER-positive patients (210 cases) Regarding the PIK3CA gene, no significant difference in iDFS was observed among ER+ patients with WT, 1MT, and 2MTs in PIK3CA ( Fig. 2A ).

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