Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML.

Stem Cell Reports · 2019 · PMC6335588 · PMID 30595549

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failed to reach statistical significanceno p-value reported

Within CTX-treated cells, Hif-1α –/– samples contained a higher LSC frequency compared with Hif-1α +/+ cells (1/26.8 versus 1/47.1 in hypoxia, and 1/40.4 versus 1/94.4 in normoxia, respectively, means from 3 independent experiments), although this failed to reach statistical significance.

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