Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice.

Front Neurosci · 2018 · PMC6336091 · PMID 30686992

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While not significant, expression of the glucocorticoid receptor (GR) showed a trend of downregulation after CUMS exposure and in TG mice (Supplementary Figure 4 ), indicating a modest effect of the CUMS paradigm on gene expression in the context of SNCA overexpression.

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