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Activation of AMPK/SIRT1 axis is required for adiponectin-mediated preconditioning on myocardial ischemia-reperfusion (I/R) injury in rats.

PLoS One · 2019 · PMC6336234 · PMID 30653603

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Interestingly, during the first 60 min of reperfusion, coronary flow tended to increase in AD group with respect to I/R group ( Fig 1C ), though this effect did not reach statistical significance.

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