In the ASCENT study, docetaxel in combination with high-dose Vitamin D was used in mCRPC patients and showed a trend toward increased SRE-free survival (planned secondary end point). 34 Time to SRE and SSE was not assessed as an exploratory end point in the most recent studies of docetaxel.
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Current concepts and trends in the treatment of bone metastases in patients with advanced prostate cancer.
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