Barely Significant
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A <i>klotho</i> gene single nucleotide polymorphism is associated with the onset of stroke and plasma klotho concentration.

Aging (Albany NY) · 2018 · PMC6339800 · PMID 30595559

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a significant trendno p-value reported
A significant trend was observed in the elderly population where plasma klotho concentration decreased as the T alleles in rs650439 increased.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.