Signatures of selection in the human antibody repertoire: Selective sweeps, competing subclones, and neutral drift.

Proc Natl Acad Sci U S A · 2019 · PMC6347681 · PMID 30622180

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showed a trendno p-value reported

In support of this, the signature of selection, as measured by the significance of Fay and Wu’s H compared with size-matched neutrally evolving lineages, showed a trend toward inverse correlation with the number of sampled sequences in the lineage ( SI Appendix , Fig.

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