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Parallel and serial mediation analysis between pain, anxiety, depression, fatigue and nausea, vomiting and retching within a randomised controlled trial in patients with breast and prostate cancer.

BMJ Open · 2019 · PMC6347855 · PMID 30679301

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Model 15 (moderation effect not included to the A-path), was chosen over model 59 (moderation effect on all paths) since separate regression analysis for the interaction of diagnosis to the relationship of the independent (pain) to the mediators (anxiety and fatigue) did not reach statistical significance.

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