We observed a slight, but statistically significant, reduction in the frequency of cells that formed CFU-F colonies in Lepr-Cre; Itga11 fl/fl mice at 2 months of age, though no significant difference was apparent at 6 months of age ( Figure 7A ).
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Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass.
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