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Treatment of Hypertensive Cardiogenic Edema with Intravenous High-Dose Nitroglycerin in a Patient Presenting with Signs of Respiratory Failure: A Case Report and Review of the Literature.

Am J Case Rep · 2019 · PMC6350673 · PMID 30662059

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During the ASCEND-HF trial, dyspnea at 6 hours and 24 hours following treatment with nesiritide, the rate of rehospitalization or death at 30 days was evaluated, which found only a small reduction in dyspnea that did not reach statistical significance [ 41 , 42 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.