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3D Organotypic Spinal Cultures: Exploring Neuron and Neuroglia Responses Upon Prolonged Exposure to Graphene Oxide.

Front Syst Neurosci · 2019 · PMC6354065 · PMID 30733671

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In s-GO we detected an increased trend of expression, when compared to controls, of CXCL2, and MCP1, T lymphocytes and monocytes recall factors, and IL6, IL10, BAFF and TNFα, cytokines responsible for pro-inflammatory responses (IL6, TNFα), regulatory function (IL10) and homeostatic B cell survival (BAFF), however the profiles of soluble factors production obtained from our analysis, did not reach statistical significance (Figure 3C ).

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