The CCR2<sup>+</sup> Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.

Staining of collagen I (indicative for fibrosis) and collagen IV (strongly expressed in liver tumors) showed reduced extracellular matrix fibers by CCL2 inhibition ( Figure 4 C ), although these differences did not reach statistical significance ( Figure 4 D ).

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