Barely Significant
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Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery.

Pharmaceutics · 2019 · PMC6359179 · PMID 30634665

Europe PMCDOI
1
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closest p · 1.0× alpha
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did not reach statistical significancep ≥ 0.05actually significant
The zeta potential of rotigotine-loaded CS NPs was less than that of placebo NPs; this small difference, which did not reach statistical significance ( p ≥ 0.05) may be due to substitution of the amino group of chitosan [ 32 ].

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