showed a trendp = 0.066
In the multivariate Cox’s regression analysis (adjusted to patient’s tumor stage, lymph node status (N-stage) and tumor grade), a high CAIX protein level in the tumor showed a trend of significance for an increased risk of death (RR = 1.7; p = 0.066) compared to patients with a low CAIX protein level in their tumor ( Table 2 , Figure 5 ).