The role of alpha defensin in prosthetic joint infection (PJI) diagnosis: a literature review.

EFORT Open Rev · 2019 · PMC6362339 · PMID 30800475

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did not reach statistical significanceno p-value reported

Bingham et al 17 obtained 100% sensitivity and 95% specificity of AD-1 assay in 57 patients and compared AD-1 assay with other clinical tests (cell count, culture, erythrocyte sedimentation rate, and C-reactive protein), showing that AD-1 assay results outperformed the other tests but did not reach statistical significance except for the sensitivity of the erythrocyte sedimentation rate.

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