A numerical trend for higher 30-day mortality with TAVI compared with medical therapy did not reach statistical significance, neither in the individual studies nor in random-effects meta-analysis (8.0% versus 4.8%; RR 1.66; 95% CI 0.90 to 3.08; I 2 = 0%).
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Comparison of transcatheter aortic valve implantation with other approaches to treat aortic valve stenosis: a systematic review and meta-analysis.
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