Barely Significant
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Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer.

Br J Ophthalmol · 2019 · PMC6362802 · PMID 29706603

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showed a trendno p-value reported
The number of drusen showing overlying foci or an altered photoreceptor layer was too small to be conclusive, but showed a trend towards an altered RPE if present.

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