Porcine vs bovine surfactant therapy for preterm neonates with RDS: systematic review with biological plausibility and pragmatic meta-analysis of respiratory outcomes.

There is a nearly significant reduction of pulmonary haemorrhage with the use of 200 mg/kg poractant-α (Fig. 4 c: p = 0.051), while this reduction becomes significant when analysis was done pooling together patients receiving different doses of poractant-α (Fig. 4 d: p = 0.038).

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