Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells.

For both the CT1 CXCL8- and CXCR1–3- knockdown CCSCs, the decrease in tumorigenicity was significant or approached significance ( Figure 5 , A and B , middle and right panels).

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