The CXCL8-CXCR1/2 Axis as a Therapeutic Target in Breast Cancer Stem-Like Cells.

Front Oncol · 2019 · PMC6373429 · PMID 30788286

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When treatment was started at day 7 following tumor cell injection and continued until day 21, a significant reduction of the number of brain metastases was observed only following combination treatment, which also showed a trend toward an inhibitory effect on metastases volume ( 12 ).

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