Similar to results from wild-type C57BL/6 mice, IP injections of WR-2721 in KPC mice caused a 30-fold enrichment of WR-1065 in the plasma compared to oral WR-2721, which did not reach statistical significance (Fig. 4e , p = 0.07).
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Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
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